Likeness: a system for rapid retrieval of similar conformation of proteins and their spatial structures |
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Authors: | Ponomarkenko M P Shindialov I Bourne P Kolchanov N A |
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Affiliation: | Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, Russia. |
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Abstract: | We report a method for estimating the conformational likeness between any two proteins. Likeness is handled in terms of stochastic geometry, fuzzy logic and decision making theories. Using the method, a computer system LIKENESS was developed. The system does "real time" searching and spatial alignment of any PDB-available proteins. LIKENESS is accessible at URL: "http:@cl.sdsc.edu/". |
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