<Emphasis Type="Italic">Pseudomonas aeruginosa</Emphasis> inhibits <Emphasis Type="Italic">in-vitro Candida</Emphasis> biofilm development |
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Authors: | HMHN Bandara JYY Yau RM Watt LJ Jin LP Samaranayake |
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Institution: | (1) Faculty of Dentistry, The University of Hong Kong, Oral Biosciences, 5/F, Prince Phillip Dental Hospital, 34, Hospital road, Sai Ying Pun, Hong Kong;(2) Faculty of Dentistry, The Department of Periodontology, The University of Hong Kong, 3/F, Prince Phillip Dental Hospital, 34, Hospital road, Sai Ying Pun, Hong Kong |
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Abstract: | Background Elucidation of the communal behavior of microbes in mixed species biofilms may have a major impact on understanding infectious
diseases and for the therapeutics. Although, the structure and the properties of monospecies biofilms and their role in disease
have been extensively studied during the last decade, the interactions within mixed biofilms consisting of bacteria and fungi
such as Candida spp. have not been illustrated in depth. Hence, the aim of this study was to evaluate the interspecies interactions of Pseudomonas aeruginosa and six different species of Candida comprising C. albicans, C. glabrata, C. krusei, C. tropicalis, C. parapsilosis, and C. dubliniensis in dual species biofilm development. |
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