Prevalence of multiple antibiotic resistance among bacterial isolates from selected poultry waste dumps in Southwestern Nigeria |
| |
Authors: | Olawale Olufemi Adelowo Folakemi Aderonke Ojo Obasola Ezekiel Fagade |
| |
Institution: | (1) Department of Pure and Applied Biology, Ladoke Akintola University of Technology, PMB 4000, Ogbomoso, Nigeria;(2) Environmental Microbiology and Biotechnology Laboratory, Department of Botany and Microbiology, University of Ibadan, Ibadan, Nigeria |
| |
Abstract: | The prevalence of multiple antibiotic resistant bacteria in the waste dumpsite of ten poultry farms in Southwestern Nigeria
was investigated. The susceptibility of 195 organisms isolated from the study sites to eight antimicrobial agents were tested
using disc diffusion method and the minimum inhibitory concentration of cloxacillin and amoxicillin determined by the agar
dilution method. Resistance to the test antibiotics ranged between 0% for gentamicin and 100% for tetracycline and ampicillin
among the organisms. Overall, 70 and 90% of the isolates from Okuku, 65.2 and 95.6% from Ogbomoso, and 46.1 and 84.6% from
Oyo had MIC above 512 μg/ml for amoxicillin and cloxacillin. Generally, drugs used in high volumes in the studied farms are
the least active against the bacterial isolates. Results of this study shows that poultry waste can serve as environmental
reservoirs of multiple antibiotic resistant bacteria and their indiscriminate dumping in the environment can expose surrounding
human populations to health risks from drug resistant zoonotic pathogens.
Part of the data presented in this paper was the subject of a presentation at the World Congress of Pharmacy and Pharmaceutical
Sciences/67TH International Congress of the International Pharmaceutical Federation (FIP), 31 August—6 September 2007, Beijing,
People’s Republic of China. |
| |
Keywords: | Antibiotics Bacteria Multiple drug resistance Poultry waste |
本文献已被 SpringerLink 等数据库收录! |
|