Growth,glucose metabolism and melanin formation in biotin-deficientAspergillus nidulans |
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Authors: | J D Desai V V Modi |
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Institution: | (1) Department of Microbiology, Faculty of Science, M.S. University of Baroda, 390 002 Baroda, India |
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Abstract: | Biotin deficiently resulted in an increased growth rate ofAspergillus nidulans. The activities of hexokinase and aldolase were not much changed during the growth cycle, but activities of glucose-6-phosphate
dehydrogenase and NADP-linked glutamate dehydrogenase increased significantly during the exponential phase. This change was
remarkable during biotin deficiency. In contrast to the higher growth rate and respiration rate during biotin deficiency the
activities of NAD(P)H oxidoreductases were low. An inverse relationship between the activity of tyrosinase and melanin content
was observed. A role of the DOPA-DOPA-quinone system in maintaining culture growth is suggested. |
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Keywords: | |
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