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A brief historical and evolutionary perspective on the origin of cellular microbiology research
Authors:Thierry Soldati,Elena Cardenal‐Mu  oz
Affiliation:Thierry Soldati,Elena Cardenal‐Muñoz
Abstract:Integrated with both a historical perspective and an evolutionary angle, this opinion article presents a brief and personal view of the emergence of cellular microbiology research. From the very first observations of phagocytosis by Goeze in 1777 to the exhaustive analysis of the cellular defence mechanisms performed in modern laboratories, the studies by cell biologists and microbiologists have converged into an integrative research field distinct from, but fully coupled to immunity: cellular microbiology. In addition, this brief article is thought as a humble patchwork of the motivations that have guided the research in my group over a quarter century.
Keywords:autophagy  cell‐autonomous defence  Dictyostelium discoideum  host‐pathogen interactions  infection  innate immunity  macrophage  metal poisoning  model organisms  Mycobacterium marinum  nutritional immunity  phagocytosis
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