Steroids from the soft coral Dendronephthya sp |
| |
| Authors: | Li Guoqiang Deng Zhiwei Guan Huashi van Ofwegen Leen Proksch Peter Lin Wenhan |
| |
| Affiliation: | State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, China. |
| |
| Abstract: | Fifteen steroids were isolated from the soft coral Dendronephthya sp., of which five are determined as new compounds, namely (22E)-3-O-beta-formylcholest-5,22-diene (1), (22E)-3-O-beta-formyl-24-methyl-cholest-5,22-diene (2), 2-ethoxycarbonyl-2-beta-hydroxy-A-nor-cholest-5-ene-4-one (3), (22E)-2-ethoxycarbonyl-2-beta-hydroxy-A-nor-cholest-5,22-diene-4-one (4), and (22E)-2-ethoxycarbonyl-2-beta-hydroxy-24-mthyl-A-nor-cholest-5,22-diene-4- one (5). 1 and 2 belonged to 3-O-formylated cholesterol analogues, and 3 to 5 are unique ring A-contracted steroids. Their structures were elucidated by extensive 2D NMR in association with IR, MS analysis. |
| |
| Keywords: | Dendronephthya sp. 3-Formyloxysterols A-nor-steroids |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
