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A model of intracellular transport of particles in an axon
Authors:Avner Friedman  Gheorghe Craciun
Affiliation:(1) Mathematical Biosciences Institute, The Ohio State University, 231 W 18th Avenue, Columbus, OH, 43210
Abstract:In this paper we develop a model of intracellular transport of cell organelles and vesicles along the axon of a nerve cell. These particles are moving alternately by processive motion along a microtubule with the aid of motor proteins, and by diffusion. The model involves a degenerate system of diffusion equations. We prove a maximum principle and establish existence and behavior of a unique solution. Numerical results show how the transportation of mass depends on the relevant parameters of the model.
Keywords:35E99  35J70  92C35
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