D-galactosamine induced changes in rat liver plasma membranes lipid composition and some enzyme activities |
| |
| Authors: | D H Petkova A B Momchilova T T Markovska K S Koumanov |
| |
| Affiliation: | Central Laboratory of Biophysics, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria |
| |
| Abstract: | The influence of D-galactosamine administration on rat liver plasma membranes lipid composition, fluidity and some enzyme activities was investigated. D-Galactosamine was found to induce an increase of the total phospholipids, the cholesterol level and membrane rigidity. In liver plasma membranes of D-galactosamine-treated rats the exogenous phospholipase A2 activity was enhanced about 2 fold, whereas the endogenous activity was slightly decreased. No alteration of the neutral sphingomyelinase activity was observed. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
