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Empirical array quality weights in the analysis of microarray data |
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| Authors: | Matthew E Ritchie Dileepa Diyagama Jody Neilson Ryan van Laar Alexander Dobrovic Andrew Holloway Gordon K Smyth |
| Institution: | (1) Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria, 3050, Australia;(2) lan Potter Foundation Centre for Cancer Genomics and Predictive Medicine, The Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, Victoria, 3002, Australia;(3) Department of Pathology, Molecular Pathology Research,The Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, Victoria, 3002, Australia |
| Abstract: | BackgroundAssessment of array quality is an essential step in the analysis of data from microarray experiments. Once detected, less reliable arrays are typically excluded or "filtered" from further analysis to avoid misleading results. |
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