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Empirical array quality weights in the analysis of microarray data
Authors:Matthew E Ritchie  Dileepa Diyagama  Jody Neilson  Ryan van Laar  Alexander Dobrovic  Andrew Holloway  Gordon K Smyth
Institution:(1) Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria, 3050, Australia;(2) lan Potter Foundation Centre for Cancer Genomics and Predictive Medicine, The Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, Victoria, 3002, Australia;(3) Department of Pathology, Molecular Pathology Research,The Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, Victoria, 3002, Australia
Abstract:

Background  

Assessment of array quality is an essential step in the analysis of data from microarray experiments. Once detected, less reliable arrays are typically excluded or "filtered" from further analysis to avoid misleading results.
Keywords:
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