Phylogenetic evidence for inter-typic recombination in the emergence of human enterovirus 71 subgenotypes |
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Authors: | Chan Yoke-Fun Sazaly AbuBakar |
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Affiliation: | (1) Department of Medical Microbiology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia |
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Abstract: | Background Human enterovirus 71 (EV-71) is a common causative agent of hand, foot and mouth disease (HFMD). In recent years, the virus has caused several outbreaks with high numbers of deaths and severe neurological complications. Several new EV-71 subgenotypes were identified from these outbreaks. The mechanisms that contributed to the emergence of these subgenotypes are unknown. |
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