饮食干预联合左卡尼汀治疗维持性血液透析营养不良的疗效观察

目的:研究饮食干预联合左卡尼汀治疗维持性血液透析营养不良的疗效。方法:选取我院2012年1月到2014年1月收治的90例维持性血液透析营养不良患者,随机分为观察组和对照组,每组45例,对照组进行常规的血液透析治疗,观察组在对照组的基础上行饮食干预联合左卡尼汀的治疗,观察并对比两组患者治疗前后的疗效。结果:观察组患者治疗后体重指数(BMI)和体重增幅显著高于对照组,差异均有统计学意义(P均0.05);观察组患者治疗后总蛋白(TP)、前白蛋白(PA)、白蛋白(Alb)显著高于对照组,血肌酐(SCr)、尿素氮(BUN)显著低于对照组,差异均有统计学意义(P均0.05);观察组患者治疗后SGA评分显著高于对照组,差异有统计学意义(P0.05)。结论:饮食干预联合左卡尼汀利于改善维持性血液透析营养不良患者的营养不良的症状,效果显著,值得临床推广。

Dietary Intervention Combined with Levocarnitine for Malnutrition Patients with Maintenance Hemodialysis

Objective:To study the curative effect of dietary intervention combined with Levocarnitine in the treatment of malnutrition atients with maintenance hemodialysis.Methods:A total of 90 maintenance patients with hemodialysis malnutrition, who were admitted to Shanghai Tongren Hospital from January 2012 to January 2014, were randomly divided into observation group(n=45) and control group (n=45). The control group was treated with routine hemodialysis therapy, while the observation group was added dietary intervention combined with Levocarnitine on the basis of control group. The curative effect in the two groups before and after treatment were compared.Results:The Body mass index (BMI) and the increase of body weight in the observation group after treatment were significantly higher than those in the control group, the differences were statistically significant (P<0.05). Total protein (TP), prealbumin(PA) and albumin(Alb) in the observation group after treatment were significantly higher than those in the control group, but the serumcreatinine (SCr) and blood urea nitrogen (BUN) were significantly lower than those in the control group, the differences were statistically significant (P<0.05); SGA score in the observation group after treatment was significantly higher than that in the control group, the difference was statistically significant (P<0.05).Conclusion:Dietary intervention combined with Levocarnitine is good for improving the symptoms of malnutrition patients with maintenance hemodialysis,and it has a significant curative effect, which is worthy of promotion in the clinical field.