绝经期女性血脂及血压水平与糖尿病骨质疏松的关系

目的：探讨绝经期女性血脂及血压与糖尿病骨质疏松发生的关系。方法：选取2014 年3 月-2015 年5 月在我院接受治疗的绝经期女性糖尿病患者100 例作为研究对象，根据骨密度不同将患者分为骨质疏松组和非骨质疏松组。检测并比较两组研究对象的血脂及血压水平，分析其与骨质疏松发生的关系。结果：骨质疏松组患者总胆固醇（TC）、三酰甘油（TG）、高密度脂蛋白胆固醇（HDL-C）及低密度脂蛋白胆固醇（LDL-C）水平均高于非骨质疏松组，差异具有统计学意义（P<0.05）；与非骨质疏松组比较，骨质疏松组患者舒张压（DBP）升高，而收缩压（SBP）降低，差异具有统计学意义（P<0.05）；Pearson相关性分析结果显示，年龄、总胆固醇（TC）及低密度脂蛋白胆固醇（LDL-C）与双股骨骨密度呈正相关关系（P＜0.05），与腰椎骨密度呈负相关关系（P＜0.05）；Logistic回归分析结果显示，年龄、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）及收缩压（SBP）是糖尿病骨质疏松发生的危险因素（P<0.05）。结论：绝经期女性糖尿病患者的年龄、总胆固醇、LDL-C 及收缩压与骨质疏松密切相关，临床应给予重视并采取有效措施进行预防。

Relationship of Blood Pressure and Lipid with Diabetic Osteoporosis forMenopausal Women

Objective:To investigate the relationship of blood pressure and lipid with the diabetic osteoporosis for menopausalwomen.Methods:100 menopausal women with diabetes who were treated in our hospital from March 2014 to May 2015 May in ourhospital were selected as the research objects, and according to the different bone density, the patients were divided into the osteoporosisgroup and non osteoporosis group. Then the blood lipids and blood pressure were detected and compared between the two groups.Results:Compared with non osteoporosis group, the total cholesterol (TC), three glycerol (TG), high density lipoprotein cholesterol(HDL-C) and low density lipoprotein cholesterol (LDL-C) of patients in the osteoporosis group were higher, and the differences werestatistically significant (P<0.05); Compared with the non osteoporosis group, the diastolic pressure (DBP) in the osteoporosis groupincreased, and the systolic blood pressure (SBP) decreased, and the differences were statistically significant (P<0.05); Pearson correlationanalysis showed that age, TC and LDL-C might be positively correlated with femoral bone mineral density (P<0.05), and negativelyrelated to lumbar bone mineral density (P<0.05); Logistic regression analysis showed that age, TC, LDL-C and SBP might be the riskfactors of diabetic osteoporosis (P<0.05).Conclusion:The age, TC, LDL-C and SBP of the patients with diabetes are closely related tothe osteoporosis, and the clinical treatment should pay more attention and take effective measures to prevent.