Application of LIBS in Detection of Antihyperglycemic Trace Elements in Momordica charantia |
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| Authors: | Nilesh K Rai Prashant Kumar Rai Shiwani Pandhija Geeta Watal A K Rai Dane Bicanic |
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| Institution: | (1) Laser spectroscopy research laboratory, Department of Physics, University of Allahabad, Allahabad, 211002, India;(2) Alternative Therapeutics Unit, Drug Discovery & Development Division, Medicinal Research Lab, Department of Chemistry, University of Allahabad, Allahabad, 211002, India;(3) Laboratory of Biophysics, Department of Agrotechnology and Food Sciences, Wageningen University, Dreijenlaan 3-Transitorium, 6703 HA Wageningen, The Netherlands |
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| Abstract: | The present study exploits the information based on concentration of trace elements and minerals in understanding the role/mechanism
of action of freeze-dried fruit powder suspended in distilled water of Momordica charantia (family: Cucurbitaceae) in diabetes treatment. Laser-induced break down spectroscopy (LIBS) spectra of plant product was
recorded under optimized experimental conditions and analyzed. Several atomic lines such as Na, K, Mg, Ca, Fe, Al, etc. have
been observed in the LIBS spectra of the above plant product. The concentrations of these minerals are determined by using
calibration-free LIBS method. Correlation between the concentration of these elements/minerals and their defined role in diabetes
management was studied in normal as well as diabetic animal models. |
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| Keywords: | Momordica charantia Diabetes LIBS Indian herbs Cucurbitaceae |
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