高寒环境实验兔骨骼肌火器伤组织病理学观察

目的:探讨高寒低温干燥自然条件下,火器伤病理组织学变化特点,为临床救治及预防冻-火器复合伤提供依据。方法:对一组实验兔,在-18℃～-22℃低温干燥自然条件下,用5.62 mm小口径手枪,距0.5cm射击双后肢,制做冻-火器复合伤模型;观察骨骼肌火器伤病理组织学改变及超微结构特征。结果:高寒低温干燥自然条件下冻-火器复合伤的病理改变,挫伤区组织以坏死为主,震动区以变性为主。提示高寒低温环境肌组织火器伤病理改变是火器与高寒低温共同引起损伤,高寒条件加剧损伤程度;而在创伤肌组织震荡区中,仍保存较多的肌性修复功能,呈现以肌巨细胞增生性为主的修复过程。结论:高寒干燥自然条件下早期脱离高寒环境,可以较好地减轻或预防冻-火器复合伤的程度。

Histopathological Observation Rabbit Skeletal Muscle Wounded by Gunshot in Alpine Environment

Objective: To explore the features of histological change in cold and drying natural conditions,and to provide the basis for clinical treatment and prevention of cold-firearm combined injury.Methods: A group of rabbits were wounded in the hind legs by 5.62 mm small caliber handgun in cold and drying natural condition(-18 ℃～-22℃).The cold-firearm combined injury model were made to observe histological change and ultrastrutural features of skeletal muscle with firearms injury.Results: The cold-firearm com-bined injury in cold and drying natural conditions showed tissue necrosis in contusion area and degeneration in the shock area.In cold temperature environment,the pathological change of muscle tissue gunshot wounds were caused together by cold and firearm,further-more cold conditions aggravated damage,and muscle tissue of the wound area in shock still had actively muscular repair,showing the gi-ant muscle cell proliferation sex-based repair process.Conclusion: In cold low-temperature drying under natural condition,away from alpine environment in the earlier,you can create a better way to reduce or prevent the extent of freezing combined injury;treatment of wounds in addition to comply with the general principles,the removal of necrotic tissue degeneration zone of retention,which will help tissue repair and reduce scar healing,retain muscle function.