恶性肿瘤患者化疗前后血糖变化的临床观察

目的:探讨化疗对恶性肿瘤患者血糖的影响。方法:取江苏省溧水县人民医院2008年1月~2011年3月收治的153例恶性肿瘤患者,采取回顾性分析方法对合并2型糖尿病的患者比例,以及化疗前、化疗中、化疗后血糖变化情况进行临床观察。结果:153例患者中,化疗前诊断糖尿病者占9.15%(14/153),未诊断糖尿病者139例,13.67%(19/139)化疗后空腹血糖升高,其中糖耐量异常者11人,占7.91%(11/39),诊病者5人,占3.60%(5/139),一过性血糖升高3人,占2.16%(3/153)。结论:恶性肿瘤患者接受化疗可以引起血糖升高,甚至出现糖耐量异常或2型糖尿病,需进一步分析原因,探索该现象与恶性肿瘤患者治疗效果和预后的关系。

The Observation to the Change of Blood Sugar Anterior-Posterior Chemotherapy of Patients with Malignant Tumor

Objective:To investigate the influence of chemotherapy to the patients with malignant tumor.Methods: To collect 153 cases of patients with malignant tumor treated in the Hospitals of Jiangsu province Lishui county between January,2008 to March,2011,take the retrospective analysis to observe the blood sugar before,between,and after chemotherapy of patients combined with Type 2 Diabetes Mellitus.Results: Among the 153 cases of patient with malignant tumor,there are 14 of them have final diagnosis of Type 2 Diabetes Mellitus,at percentage of 9.15%,and the others do not have final diagnosis of Type 2 Diabetes Mellitus.But after chemotherapy,19 of them show higher blood-fasting sugar,at percentage of 13.67%,11 cases show glucose tolerance abnormal,at percentage of 7.91%,and 5 cases have treatment,at percentage of 3.60%.3 cases have tentative higher blood sugar,at percentage of 2.16%.Conclusion: The patients with malignant tumor treated with chemotherapy can rise their blood sugar levels,and even glucose tolerance abnormal or Type 2 Diabetes Mellitus,we have to find the reason further,and research the relationship between the Treatment Effectiveness and Prognosis of patients.