Caldesmon association with smooth muscle thin filaments isolated in the presence and absence of calcium |
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Authors: | W Lehman |
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Abstract: | Thin filaments isolated from chicken gizzard smooth muscle in either the presence or the absence of Ca2+ possess identical caldesmon contents. Hence, a 'flip-flop' mechanism, involving Ca2+-dependent association and dissociation of caldesmon and thin filaments, does not appear to operate in vivo and is an unlikely model for caldesmon function. |
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