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Toxic effect on human spermatozoa by Chlamydia trachomatis purified lipopolysaccharide
Authors:Francesco Galdiero  Linda Sommese  Fernanda Gorga  Emilia Galdiero  Antonietta Rizzo  Maria Ajello
Affiliation:Istituto di Microbiologia, Facoltàdi Medicina e Chirurgia, Seconda Universitàdegli Studi di Napoli, Larghetto S. Aniello a Caponapoli, 2, 80138 Naples, Italy; Istituto di Microbiologia, Facoltàdi Farmacia, Universitàdegli Studi di Roma, Rome, Italy; CNR, Area di Ricerca, Naples, Italy
Abstract:Abstract We have investigated the effect that lipopolysaccharide extracted from Chlamydia trachomatis has on human spermatozoa. A lipopolysaccharide of 0.1 μg ml−1 caused a spermatozoa mortality rate of 65±4% evaluated by eosin exclusion test. The toxic activity occurred rapidly even after brief incubation times, reaching the maximum (100% mortality) within 60 min.
Keywords:Chlamydia trachomatis    Lipopolysaccharide    Spermatozoa
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