Biochemical effects of garlic protein on lipid metabolism in alcohol fed rats |
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Authors: | Rajasree C R Rajamohan T Augusti K T |
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Institution: | Department of Biochemistry, University of Kerala, Thiruvananthapuram, India. |
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Abstract: | Garlic protein is a very good hypolipidemic agent. In the present study the water soluble protein fraction of garlic was investigated for its effect on hyperlipidemia induced by alcohol (3.76 g/kg. body wt./day). The hypolipidemic action is mainly due to an increase in cholesterol degradation to bile acids and neutral sterols and mobilization of triacyl glycerols in treated rats. Garlic protein (500 mg./kg body wt./day) showed significant hypolipidemic action comparable with a standard dose of gugu-lipid (50 mg./kg. body wt./day). |
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