A highly conserved 530 base-pair repeated DNA sequence specific for Bordetella pertussis |
| |
Authors: | Insoo Park William Saurin Agnes Ullmann |
| |
Affiliation: | Unitéde Biochimie des Régulations Cellulaires, France;Unitéde Programmation Moléculaire et Toxicologie Génétique, Institut Pasteur, Paris, France |
| |
Abstract: | Abstract The genome of Bordetella pertussis contains a strictly conserved 530 base-pair (bp) repeated sequence present in about 70 to 80 copies and accounting for approximately 1% of the bacterial genome. The repeated element, whose complete nucleotide sequence has been determined, is specific for B. pertussis DNA; it could be detected neither in closely related Bordetella strains nor in other bacterial or eukaryotic DNAs. The repeated sequence is not associated with the control of the expression of virulence determinants. |
| |
Keywords: | Repeated DNA sequence Bordetella pertussis Virulence determinant |
|