Abstract: | Objective: Using oligonucleotide microarrays HG-U133A, we here studied the expression levels of genes that could differentiate between patients with myocardial infarction (MI) from healthy subjects, as well as to select among such genes those that seem crucial for manifestation of cardiovascular diseases.Materials and methods: The microarray study was conducted using material derived from blood samples collected in 17 individuals.Results: Analysis of gene expression data from 17 microarrays allowed identification of 28 genes strongly differentiating the examined groups.Conclusion: The differentiating genes that we tracked down indicate possible linkage with atherosclerotis and could be a prognostic marker for development of cardiovascular diseases. |