Abstract: | AbstractRationale: Metabolic syndrome, inflammatory and vascular injury markers measured in serum after World Trade Center (WTC) exposures predict abnormal FEV1. We hypothesized that elevated LPA levels predict FEV1?Methods: Nested case-control study of WTC-exposed firefighters. Cases had FEV1?Results: LPA and ApoA1 levels were higher in cases than controls and predictive of case status. LPA increased the odds by 13% while ApoA1 increased the odds by 29% of an FEV1?Conclusions: Elevated LPA and ApoA1 are predictive of a significantly increased risk of developing an FEV1?
|