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Role of Ca2+ in regulating the serotonin-dependent synapse between P and R-cells of leech segmented ganglion]
Authors:G V Maksimov  Sh Chatterdzhi  A L Kleinhaus  A B Rubin
Institution:Lomonosov Moscow State University, Russia.
Abstract:Changes in the membrane-associated Ca2+ concentration and viscosity of the plasmatic membrane of P- and R-cells segmented ganglia of medicinal leech upon a variation of extracellular serotonin concentration were investigated. It is shown that the transmission of rhythmic excitation from P- to R-cells is due to the formation of the serotonin-dependent synapse and affects the distribution of the membrane-associated Ca2+ and intracellular processes controlling the viscosity of the membrane.
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