Studies on cell adhesion. II. Adhesion of cells to surfaces of diverse chemical composition and inhibition of adhesion by sulfhydryl binding reagents |
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| Authors: | F Grinnell M Milam P A Srere |
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| Affiliation: | 1. Department of Physics, PSG College of Arts and Science, Coimbatore, 641 014, Tamilnadu, India;2. Department of Mechanical Engineering, Kumaraguru College of Technology, Coimbatore, 641035, Tamilnadu, India;3. Department of Physics, Dr. N.G. P. Institute of Technology, Coimbatore, 643 048, India;1. Institute of Hybrid Materials, National Center of International Joint Research for Hybrid Materials Technology, National Base of International Sci. & Technology Cooperation on Hybrid Materials, Qingdao University, 308 Ningxia Road, Qingdao, 266071, People’s Republic of China;2. Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, Colorado, 80523, USA;3. Department of Medical Oncology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, 266003, People’s Republic of China;1. G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far East Branch of the Russian Academy of Sciences, Prospect 100-let Vladivostoku, 159, Vladivostok 690022, Russia;2. Medical Association of the Far East Branch of the Russian Academy of Sciences, Vladivostok, St. Kirova, 95, 690022, Russia;1. Doctoral student, Department of Dental Materials and Prosthodontics, Ribeirão Preto Dental School, University of São Paulo, Ribeirão Preto, Brazil;2. Doctoral student, Department of Dental Materials and Prosthodontics, Ribeirão Preto Dental School, University of São Paulo, Ribeirão Preto, Brazil;3. Associate Professor, Department of Materials Engineering, Federal University of São Carlos (UFSCAR), São Carlos, Brazil;4. Associate Professor, Department of Dental Materials and Prosthodontics, Ribeirão Preto Dental School, University of São Paulo, Ribeirão Preto, Brazil;5. Professor, Department of Restorative Dentistry, Ribeirão Preto Dental School, University of São Paulo, Ribeirão Preto, Brazil;6. Doctoral student, Department of Materials Engineering, Federal University of São Carlos (UFSCAR), São Carlos, Brazil;7. Professor, Laboratory of Solid State Chemistry, State University of Campinas (UNICAMP), Campinas, Brazil;8. Private practice, Campinas, Brazil;9. Associate Professor, Department of Dental Materials and Prosthodontics, Ribeirão Preto Dental School, University of São Paulo, Ribeirão Preto, Brazil |
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| Abstract: | Rat hepatoma cells are able to adhere to many surfaces of diverse chemical compositions. Adhesion to different kinds of surfaces was inhibited when cells were treated with sulfhydryl binding reagents, but not with inhibitors of transport, respiration, and glycolysis. Inhibition of adhesion by p-mercuribenozate and arsenite was reversible; inhibition by HgCl2, iodoacetate and N-ethylmaleimide was not reversible. Cell adhesion is discussed in terms of current theories of chemical adhesion. |
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