等离子经尿道前列腺电切对患者生活质量的影响

目的:探讨等离子经尿道前列腺电切(PKRP)和常规经尿道前列腺电切(TURP)对良性前列腺增生(BPH)患者生活质量的影响。方法:采取前瞻性随机对照的方法将105名需要手术治疗的BPH患者随机分成二组:即TURP组51例,PKRP组54例。使用IPSS、QOL和WHOQOL-BREF量表,分别在术前、术后第1、6和12个月对患者的LUTS和生活质量进行评估。结果:TURP组和PKRP组患者的生活质量在术后6个月得到明显改善。TURP组术后第6个月的IPSS、QOL和WHOQOL-BREF评分分别为10.4±2.6,1.7±0.6和55.1±7.4,术后第12个月的IPSS、QOL和WHOQOL-BREF评分分别为11.4±2.6,1.7±0.5和55.2±6.9,均比术前(21.5±5.3,5.3±0.9和52.4±7.0)有明显改善。PKRP组术后第6个月的IPSS、QOL和WHOQOL-BREF评分分别为9.8±2.4,1.5±0.4和57.9±8.1,术后第12个月的IPSS、QOL和WHOQOL-BREF评分分别为10.6±2.2,1.7±0.5和56.3±6.2,均比术前(21.3±6.1,5.2±1.0和55.0±8.8)有明显改善。结论:TURP和PKRP术后第6个月患者的生活质量得到持续改善,WHO-QOL-BREF可以作为评价TURP和PKRP对BPH患者生活质量影响的可靠测量工具。

Effects of Transurethral Resection of Prostate and Plasmakinetic Resectionof Prostate on Patients' Health Related Quality of Life

Objective: To investigate the effects of transurethral resection of prostate and plasmakinetic resection of prostate on health related quality of life(HRQOL) and urinary symptoms in patients with benign prostatic hyperplasia(BPH).Methods: In this prospective randomized study,105 patients with BPH were recruited.51 patients underwent TURP and 54 patients underwent PKRP.Pa-tients completed two validated questionnaires: the International Prostate Symptom Score(IPSS) and the associated QOL index.These were completed preoperatively,at 1,6,and 12 months postoperatively.Results: The HRQOL of patients who underwent TURP and PKRP for BPH had significantly improved 6 months after their operation.The IPSS Scores,QOL index and total WHOQOL-BREF scores at 6 months(10.4±2.6,1.7±0.6,55.1±7.4),and 12 months(11.4±2.6,1.7±0.5,55.2±6.9) improved than that in preoperative(21.5±5.3,5.3±0.9,52.4±7.0) in TURP group.IPSS Scores,QOL index and total WHOQOL-BREF scores at 6 months(9.8±2.4,1.5± 0.4,57.9±8.1),and 12 months(10.6±2.2,1.7±0.5,56.3±6.2) improved than that in preoperative(21.3±6.1,5.2±1.0,55.0±8.8) in PKRP group respectively.Conclusions: Improvement in HRQOL was observed 6 months after TURP and PKRP in patients with BPH.This study demonstrates that the WHOQOL-BREF is a suitable HRQOL instrument for older people with BPH accepted TURP and PKRP procedures.