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Encoding the states of interacting proteins to facilitate biological pathways reconstruction
Authors:Alberto Termanini  Paolo Tieri  Claudio Franceschi
Affiliation:(1) 'L. Galvani' Interdepartmental Center, University of Bologna, Via San Giacomo 12, 40126 Bologna, Italy;(2) Department of Experimental Pathology, University of Bologna, Via San Giacomo 12, 40126 Bologna, Italy
Abstract:

Background  

In a systems biology perspective, protein-protein interactions (PPI) are encoded in machine-readable formats to avoid issues encountered in their retrieval for the reconstruction of comprehensive interaction maps and biological pathways. However, the information stored in electronic formats currently used doesn't allow a valid automatic reconstruction of biological pathways.
Keywords:
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