Modification of supported lipid membranes by atomic force microscopy |
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| Authors: | Susan L Brandow David C Turner Banahalli R Ratna and Bruce P Gaber |
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| Institution: | Center for Biomolecular Science and Engineering, Naval Research Laboratory, Washington, DC 20375-5000 USA |
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| Abstract: | The atomic force microscope (AFM) was used to structurally modify supported lipid bilayers in a controlled quantitative manner. By increasing the force applied by the AFM tip, lipid was removed from the scanned area, leaving a cut through the lipid bilayer. Cuts were repaired with the AFM by scanning the region with a controlled force and driving lipid back into the cut. A slow self-annealing of cuts was also observed. |
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