TRANSFORMATION OF SWINE PEPSINOGEN INTO SWINE PEPSIN BY CHICKEN PEPSIN |
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Authors: | Roger M. Herriott Quentin R. Bartz John H. Northrop |
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Affiliation: | From the Laboratories of The Rockefeller Institute for Medical Research, Princeton, New Jersey, and the Institute of Experimental Biology, University of California, Berkeley, California |
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Abstract: | Activation of swine pepsinogen with chicken pepsin results in the formation of swine pepsin. Activation of chicken pepsinogen with swine pepsin results in the formation of chicken pepsin. The structure responsible for the species specificity of the enzyme is therefore present in the inactive precursor. |
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