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Identification of Orthosteric and Allosteric Site Mutations in M2 Muscarinic Acetylcholine Receptors That Contribute to Ligand-selective Signaling Bias |
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| Authors: | Karen J Gregory Nathan E Hall Andrew B Tobin Patrick M Sexton and Arthur Christopoulos |
| Institution: | From the ‡Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, Victoria 3052, Australia and ;the §Department of Cell Physiology and Pharmacology, University of Leicester, Leicester LE1 9HN, United Kingdom |
| Abstract: | |
| Keywords: | Cholinergic Receptor Drug Action G Protein-coupled Receptors (GPCR) Neurochemistry Neurotransmitter Receptors Receptor Structure-function |