Two-component signal transduction systems in eukaryotic microorganisms |
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| Authors: | Loomis W F Kuspa A Shaulsky G |
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| Institution: | Center for Molecular Genetics, Department of Biology, University of California, San Diego, La Jolla, CA 92093, USA. |
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| Abstract: | Conserved signal transduction pathways that use phosphorelay from histidine kinases through an intermediate transfer protein (H2) to response regulators have been found in a variety of eukaryotic microorganisms. Several of these pathways are linked to mitogen-activated protein kinase cascades. These networks control different physiological responses including osmoregulation, cAMP levels and cellular morphogenesis. |
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| Keywords: | Abbreviations: HOG high osmolarity glycerol response MAP mitogen-activated protein PKA protein kinase A |
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