(1) School of Biosciences, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
Abstract:
Background
The Scar/WAVE family of proteins mediates signals to actin assembly by direct activation of the Arp2/3 complex. These proteins have been characterised as major regulators of lamellipodia formation downstream of Rac activation and as members of large protein complexes.
