胎膜早破产妇羊水细菌培养及药敏结果分析

目的 分析胎膜早破(PROM)产妇羊水感染细菌的分布特点和耐药情况,以探讨PROM的病原学特征,并为围产期感染的用药提供科学的指导.方法 对2010年4月至2010年7月广东省妇幼保健院产科送检的199例PROM产妇羊水标本进行细菌培养,并以法国梅里埃的全自动细菌鉴定药敏系统(VITEK-2 compact)对分离出的...

Analysis of distribution and antibiotic resistance of positive results of amniotic fluid cultures from women with premature rupture of membranes

Objective To study the distribution and drug resistance of pathogenic bacteria in amniotic fluid sample from women with premature rupture of membranes for rational use of antibiotics in clinic.Method 199 amniotic fluid samples of women with premature rupture of membranes from maternity department of our hospital from April 2009 to July 2010 were cultured;pure strains were isolated and identified.Drug-susceptibility tests were done by VITEK-2 automicroscan.Result Among the 199 amniotic fluid samples,19 were infected by bacteria.The total detection rate was 9.55%.The infection of G-bacteria accounted for 68.4%,whereas G＋ bacteria 31.6%.The strain with the highest isolating rate was E.coli（57.9%）.The antibiotic sensitivity of E.coli to ampicillin were low（50%）.Conclusion Gram-Negative bacillis are the main pathogens isolated in amniotic fluid samples of women with premature rupture of membranes.It is important to use antibiotics rationally according to drug sensitivity test and the feature of Perinatal infection.