Whole-mount in situ hybridization to mouse embryos |
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Authors: | Correia K M Conlon R A |
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Affiliation: | Department of Genetics, Case Western Reserve University, Cleveland, Ohio 44106-4955, USA. kmc@stowers-institute.org |
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Abstract: | The mouse is well-established as the major animal model for the study of mammalian development. Rapid progress in large-scale cDNA and also genomic sequencing projects is identifying new mouse genes at an unprecedented rate. As a first step toward understanding the function of these novel genes, it is important to determine their developmental expression pattern. Here we provide a reliable, sensitive method for whole-mount in situ hybridization using the mouse embryo. |
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