The structure of melittin in lipid bilayer membranes |
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| Authors: | AF Drake RC Hider |
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| Institution: | 1. Department of Chemistry, King''s College, Strand, London, W.C.2 U.K.;2. Department of Chemistry, Essex University, Colchester, Essex U.K. |
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| Abstract: | 0.15 M inorganic phosphate dramatically increased the α-helix content of melittin in aqueous solution.When melittin interacted with egg yolk phosphatidylcholine liposomes in the absence of inorganic phosphate, it was converted to an α-helix rich form, as postulated by Dawson et al. (Dawson, C.R., Drake, A.F. Helliwell, J. and Hider, R.C. (1978) Biochim. Biophys. Acta 510, 75–86). |
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| Keywords: | Melittin structure α-Helix content Lipid-protein interaction (Bilayer) |
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