Selective destruction of 5-hydroxytryptamine receptors by neuraminidase |
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| Authors: | Terence Dalton |
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| Affiliation: | Department of Zoology, Westfield College, Kidderpore Avenue, London NW3 7ST U.K. |
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| Abstract: | The responses of isolated frog skin to 5-hydroxytryptamine (increased active sodium transport and decreased passive chloride permeability) are diminished by incubation with the enzymes neuraminidase and N-acetylneuraminic acid aldolase but only in the absence of Ca2+ and presence of EDTA. The responses induced by oxytocin, adrenalin and aldosterone are unaffected by enzyme treatment. |
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| Keywords: | 5-Hydroxytryptamine receptor Neuraminidase (Frog skin) |
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