The cytological behavior of a human ring-chromosome |
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| Authors: | Ulla Gripenberg |
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| Institution: | (1) Institute of Genetics, University of Helsinki and the Rinnekoti Institution for Mentally Retarded, Helsinki |
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| Abstract: | A ring chromosome derived from group 17–18 was found in a mentally retarded girl. The ring shows considerable variability. With respect to the size the ring is enlarged in 9% of the cells. In 19% of the cells the ring is eliminated; in these cells the chromosome number is only 45. The elimination of the ring has been studied. There are cytological indications of two simultaneous mechanisms: lagging and destruction of complex unstable structures. |
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