Epithelial cell movements and interactions in limb, neural crest and vasculature. |
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Authors: | C Tickle M Altabef |
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Affiliation: | Department of Anatomy and Physiology, University of Dundee, The Wellcome Trust Building, Dow Street, Dundee, DD1 5EH, UK. c.a.tickle@dundee.ac.uk |
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Abstract: | Formation of the thickened apical ectodermal ridge of developing vertebrate limbs appears to be a complex process. Direct connections to molecular controls of cell migratory machinery have been shown for first time in neural crest migration. New unsuspected roles are emerging for ephrin ligand/Eph receptor signalling in vascular morphogenesis. |
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