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Phytochemical and biological studies of Abies species
Authors:Yang Xian-Wen  Li Su-Mei  Shen Yun-Heng  Zhang Wei-Dong
Institution:Department of Natural Product Chemistry, School of Pharmacy, Second Military Medical University, 325 Guohe Road, 200433 Shanghai, PR China.
Abstract:In the present review, the literature data on the phytochemical and biological investigations on the genus of Abies are summarized with 110 references. Up to now, 277 compounds were isolated from 19 plants of Abies species. The chemical constituents are mostly terpenoids, flavonoids, and lignans, together with minor constituents of phenols, steroids, and others. The crude extracts and metabolites have been found to possess various bioactivities including insect juvenile hormone, antitumor, antimicrobial, anti-ulcerogenic, anti-inflammatory, antihypertensive, antitussive, and CNS (central nervous system) activities.
Keywords:Abies species  Terpenoids  Flavonoids  Lignans  Steroids  Insect juvenile hormone  Antitumor activity  Antimicrobial activity  Anti‐inflammatory activity  Antihypertensive activity
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