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The demonstration of subtype (D or Y)-specific determinants on the surface of the presumed hepatitis B virus.
Authors:G Hess  J W Shih  P M Kaplan  J L Gerin
Abstract:Dane particles isolated from the sera of HBsAg/ad and HBsAg/ay carriers were reacted with monospecific antibodies to the d and y subtype-specific determinants of HBsAg/. Dane particles from HBsAg/ad expressed the d determinant on their surfaces and those from HBsAg/ay sera contained the y specificity. Both complete (DNA-P and HBcAg) and defective (HBcAg alone) Dane particles expressed the subtype-specific determinants.
Keywords:
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