Abstract: | The dynamics and intensity of radiolabelled carbon incorporation from 14C] putrescine into homocarnosine in the brains of rats of various age have been studied. In the brains of 1-, 7-, and 2-day-old rats putrescine is the main GABA source for homocarnosine synthesis. In the brains of 14- and 31-day-old animals the GABA formed from glutamic acid participates in homocarnosine synthesis alongside with putrescine. In the brains of adult rats the rate of 14C] incorporation from glutamic acid into homocarnosine is 7 times as low as that of 14C] incorporation from putrescine. |