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Nicotinic acid inhibits thromboxane synthesis in platelets |
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| Authors: | JE Vincent FJ Zijlstra |
| Institution: | Department of Pharmacology, Erasmus University Rotterdam, P.O. Box 1738, Rotterdam, The Netherlands |
| Abstract: | The formation of thromboxane A2 by phospholipase A2 in rat platelets is inhibited by nicotinic acid. The synthesis of PGE2 and PGF2α is increased.Nicotinic acid inhibits collagen-induced aggregation in rat platelets. |
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