A crystalline saponin with anti-tumor activity from entada phaseoloides |
| |
| Authors: | Wen Chih Liu Max KugelmanRichard A Wilson Koppaka V Rao |
| |
| Institution: | The John L. Smith Memorial for Cancer Research, Pfizer & Co., Inc., Maywood, New Jersey, U.S.A. |
| |
| Abstract: | A crystalline saponin, isolated from the seed kernels of Entada phaseoloides, has the tentative empirical formula C45H82O27. Acid hydrolysis yeilds a crystalline sapogenin C30H48O5 which appears to be identical with entagenic acid, together with arabinose and xylose. The saponin shows significant activity against Walker 256 carcinosarcoma in rats. |
| |
| Keywords: | Entada phaseoloides Leguminosae saponin entagenic acid anti-tumor activity |
| 本文献已被 ScienceDirect 等数据库收录！ |
