Developmental pattern of cysteine sulphinic acid transaminase activity in some areas of mice nervous system |
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Authors: | MM Gabellec M Recasens P Mandel |
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Institution: | 1. Centre de Neurochimie du CNRS, Faculté de Médecine, 11, rue Humann, 67085 Strasbourg Cedex, France;2. Institut de Chimie Biologique, Faculté de Médecine, 11, rue Humann, 67085 Strasbourg Cedex, France |
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Abstract: | Cysteine sulphinic acid (CSA), a key intermediate in the major pathway of taurine metabolism, is catabolised by cysteine sulphinic acid decarboxylase (CSA-D) to hypotaurine and by the cysteine sulphinic acid transaminase (CSA-T) to glutamate. To continue earlier studies about the latter enzyme, the CSA-T activity was measured in the developing olfactory bulb, cerebellum, whole brain and retina of C57/B16 and C3H/He inbred mice. Differences in the developmental pattern between these two strains of mice in the retinae and in the olfactory bulb were observed. The significance of the differences is discussed. |
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