Human phosphoglycolate phosphatase (PGP) E.C.3.1.3.18: Linkage analysis |
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Authors: | G Siebert A Amorim J Kömpf |
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Institution: | (1) Institut für Anthropologie und Humangenetik der Universität Tübingen, Wilhelmstrasse 27, D-7400 Tübingen, Federal Republic of Germany |
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Abstract: | Summary Linkage data on phosphoglycolate phosphatase (PGP) E.C.3.1.3.18 and 26 other human genetic markers are presented. One hundred and one families from the southwestern area of Germany were tested. Close linkage between PGP and the following markers could be ruled out: AB0, acP, ADA, GPT, PGM1, GLO, HLA, and PGM3. There is some evidence for possible linkage with MNSs, Rh, Gm and EsD. Family segregation data confirm the hypothesis formerly established by Barker and Hopkinson: three common alleles PGP1, PGP2 and PGP3 at an autosomal locus PGP.Supported by the Deutsche ForschungsgemeinschaftSupported by DAAD and Portuguese Inst. for Scientific Research (INIC) |
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