The vertebrate organizer: structure and molecules |
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Authors: | Patrick Lemaire Laurent Kodjabachian |
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Institution: | aP. Lemaire and L. Kodjabachian are in the IBDM, Laboratoire de Génétique et Physiologie du Développement, CNRS UMR 9943, Campus de Luminy, case 907, F-13288 Marseille Cedex 9, France |
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Abstract: | Since the identification of the first organizer gene, goosecoid, more than 15 organizer-specific genes have been characterized. Here, we present our current understanding of the roles of these molecules in amphiabians, fish and amniotes and show how their identification has confirmed Spemann's original proposition that the vertebrate organizer is subdivided into separate domains: the head, trunk and tail organizers. |
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