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Omnipotent RNA
Authors:Spirin Alexander S
Affiliation:Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Moscow Region, Russia. spirin@vega.protres.ru
Abstract:The capability of polyribonucleotide chains to form unique, compactly folded structures is considered the basis for diverse non-genetic functions of RNA, including the function of recognition of various ligands and the catalytic function. Together with well-known genetic functions of RNA – coding and complementary replication – this has led to the concept of the functional omnipotence of RNA and the hypothesis that an ancient RNA world supposedly preceded the contemporary DNA–RNA–protein life. It is proposed that the Woese universal precursor in the ancient RNA world could be a cell-free community of mixed RNA colonies growing and multiplying on solid surfaces.
Keywords:Non-coding RNA   RNA folding   RNA recombination   RNA world   RNA colony   Universal precursor
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