Mungin, a novel cyclophilin-like antifungal protein from the mung bean |
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Authors: | Ye X Y Ng T B |
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Affiliation: | Department of Biochemistry, Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China. |
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Abstract: | A protein designated mungin, isolated from mung bean (Phaseolus mungo) seeds, possessed activity against the fungi Rhizoctonia solani, Coprinus comatus, Mycosphaerella arachidicola, Botrytis cinerea, and Fusarium oxysporum. The 18-kDa protein also possessed a novel N-terminal sequence with similarity to cyclophilins. It exerts an inhibitory action against alpha- and beta-glucosidases suppresses [(3)H]thymidine in corporation by mouse splenocytes. |
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