Karyotypic variation in susceptibility to hemolytic anemia and idiopathic eosinophilia of owl monkeys,Aotus trivirgatus |
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Authors: | M. F. Beland R. T. Bronson N. S. F. Ma K. W. McIntyre P. K. Sehgal T. L. Keadle |
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Affiliation: | (1) Harvard Medical School, New England Regional Primate Research Center, One Pine Hill Drive, 01772 Southborough, Massachusetts, U.S.A.;(2) School of Veterinary Medicine, Louisiana State University, 70893 Baton Rough, Louisiana, U.S.A. |
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Abstract: | Hematologic data gathered over a period of 4.8 years from 196 owl monkeys,Aotus trivirgatus, were analyzed to find if karyotypic differences existed. It was found that none of 30 animals of karyotypes K-I and K-VI developed hemolytic anemia, whereas 46 of 99 animals of K-II, K-III and K-IV did (p<0.005). Analysis of hemograms of normal owl monkeys showed that mean percent eosinophils varied markedly, K-I monkeys having lowest counts, 3.2%, and K-VI animals having the highest, 33%. These results establish that idiopathic eosinophilia and hemolytic anemia in this species are probably unrelated but susceptibility to both has a strong genetic component. |
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