Effect of immunization to cholecystokinin fragment (30-33) on the behavior of albino rats |
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| Authors: | Danilova R A Rud'ko O I Korotkova T M Obukhova M F Ashmarin I P |
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| Institution: | Moscow State University, Vorobyevy Gory. |
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| Abstract: | Active immunisation of albino rats by the BSA-conjugated CCK-4 induced formation of antibodies to the CCK-4 and some long-term changes of the rat behaviour. These changes were contrary to anxiogenic effect of the CCK-4 and demonstrated an anxiolytic effect of the immunisation. The data obtained suggest a possibility of an immunocorrection of pathological anxiety and fear by an inverse immunoregulation. |
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