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Biochip detection of KRAS,BRAF, and PIK3CA somatic mutations in colorectal cancer patients
Authors:Emelyanova  M. A.  Amossenko  F. A.  Semyanikhina  A. V.  Aliev  V. A.  Barsukov  Yu. A.  Lyubchenko  L. N.  Nasedkina  T. V.
Affiliation:1.BIOCHIP-IMB Ltd., Moscow, 117312, Russia
;2.Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia
;3.Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow, 115478, Russia
;4.Medical Genetic Research Center, Moscow, 115478, Russia
;
Abstract:Molecular Biology - Somatic mutations of KRAS, PIK3CA, and BRAF cause insensitivity of colorectal tumors to therapy with anti-EGFR monoclonal antibodies, necessitating a genetic testing prior to...
Keywords:
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