"TORCing" neutrophil chemotaxis |
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| Authors: | Charest Pascale G Firtel Richard A |
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| Institution: | University of California, San Diego, La Jolla, 92093-0380, USA. |
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| Abstract: | During cell migration, chemoattractant-induced signaling pathways determine the direction of movement by controlling the spatiotemporal dynamics of cytoskeletal components. In this issue of Developmental Cell, Liu et?al. report that the target of rapamycin complex 2 (TORC2) controls cell polarity and chemotaxis through regulation of both F-actin and myosin II in migrating neutrophils. |
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